Water Cooler Wisdom

Everything that is really great and inspiring is created by the individual who can labor in freedom. --Albert Einstein

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Location: NE Minneapolis, Minnesota, United States

Everything that is really great and inspiring is created by the individual who can labor in freedom. --Albert Einstein

Wednesday, July 19, 2006

Grounding the Stem Cell Debate - Revisited

I've been pre-occupied the last week or two (more on that later).

In light of the recent congressional debate, I thought it would be good to revisit this post (updated with revisions)...


There are few issues more morally complex than the issue of stem cell research. Multi-faceted arguments exist on both sides. This moral complexity requires that the debate should be framed as clearly, factually and honestly as possible. The very question of stem cell research begs an emotional response, but restraint and objectivity will lead to better law. All too often, the arguments we hear are grounded in hope rather than reason or in misconception rather than fact. Below are some common dangers.

Hyperbolie - We hear constant claims embryonic stem cell research will lead to the cure for Alzheimer's, Parkinson's, diabetes, cystic fibrosis, some cancers and a myriad of other diseases. Call me a skeptic, but the last thing that claimed to cure so many ailments was Uncle Zeke's Magical Snake Oil Elixer. Sure there are possiblities, but very little in the way of measureable results. There is still an issue of embryonic stem cell stability. The cells have a tendancy to break down or mutate. Many of those out front on this discussion are those who have lived with one of the potentially cureable diseases. While I feel for them, they certainly are not the most objective sources.

Sloppiness and Lack of Understanding by the Media -
This article from Rueters sites another falicy without checking the facts.

"Critics of the embryonic stem cell bill center much of their efforts on alternative legislation that would fund experimental means of deriving stem cells without destroying a human embryo...
But those methods are more preliminary and speculative, and would likely take much longer to yield any therapies or cures for crippling human diseases, several scientists told a Senate hearing earlier this week."

The alternative methods included are adult stem cell and cord blood stem cell research. The truth is the exact opposite of what is stated above. While embryonic stem cells have yielded little to no concrete results, there have already been some tremendous successes using cord tblood stem cells to fight very crippling disease in humans. Some the best work is happening right here in Minnesota. The University of Minnesota is a world leader in using cord blood stem cell treatments for cancer treatments with a very impressive success rate.

Lack of Clarity - To be clear, we need to make a distinction between "stem cell research" and the more specific "embryonic stem cell research". As stated above not all stem cell research involves the destruction of embryos. Not all violates a pro-life stance.

Honesty and Consistency - I greatly respect the pro-life argument, however there are two issues that need to be addressed honestly. First, by striving to save one human life (a living embryo), it's possible (but not yet known) that another life will be shortened. Second, the Spector bill proposes using the 400,000 embryos that would be left-over from in vitro fertilization procedures. Most of these would otherwise be destroyed. To be truly consistent with the pro-life position, it is the creating of embroys (that would either be destroyed or used for research) that should be opposed, not how they are disposed of once they exist. The real fight should be against such in vitro fertilization procedures.

Not Funding Does Not Equal Not Doing or Not Allowing - A vote against Federal funding for embryonic stem cell research does not mean that any funding is prohibited or that it will not happen, just that the funding would have to come from state or private sources or state funding. And, it certainly does not mean that the research is made illegal. If there really are many benefits to the research on the horizon, that means huge profits on the horizon for pharma companies. These companies are looking to the taxpayers to absorb the risk while they later reap the profits. If the potential is there, the market will work and the investment in research will happen without funding.

6 Comments:

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11/13/2005 3:21 AM  
Anonymous Anonymous said...

I find your comments, in my opinion, somewhat contradictory in the second paragraph under "Sloppiness...". How do you think the U of M got to the point of being able to determine cancer treatment from stem cells? Years and years of research. Perhaps I'm taking your viewpoint strictly as an assumption that nothing good could possibly come from embryonic stem cells, but (pardon the phrase), in the beginning, all medical applications had to be tested and went through similar phases of failure, etc, particularly medications.

Look at the current pharmacotherapy for AIDS of antiretrovirals and protease inhibitors. For years, drugs were trialed and tested. Meds were thrown out due to horrific side effects, incompatabilities with other treatments, causation of new maladies, and even death. Finally a cocktail of 8-10 pills was developed and showed the most remarkable results in both viral load reduction and increase of CD4 cell count. Patients on this regimen were taking these 3-4 times a day. Can you imagine 40 pills a day for ONE disease? Throw on the typical other meds an given person takes and your looking at 45-50 pills a day! Eventually those 10 were narrowed to 3 as longtudinal studies suggested some were more effective than others and some just did nothing but complicate the metabolic process. Much better right? Now there is Atripla. One pill, once a day.

The FDA is constantly looking at new treatments and medications, making recommendations after only a few pilots or 3-5 years of research and then retracting its recommendations because an even longer study proved otherwise. Case in point, red wine. For years, closed-minded researchers said alcohol is bad. Then on person did a 15 year case study of French patients who consumed regular, daily amounts of alcohol. Result? Less CVD, hypertension, and increased longevity from the routine relaxation of cardiac muscle. So the FDA and AMA started recommending 1-2 glasses of red wine a day.

Ok I'm done. Just my opinion so no need to jump on me like with the science v. religion post!
:)

7/19/2006 8:16 AM  
Blogger Nordeaster said...

My point under "slopiness" is really focused on the misleading (intentionally?) reporting. Don't say alternative methods are more preliminary and speculative, when in fact the opposite is true.

No, I'm not saying nothing good can come from the study of embryonic stem cell research. It very well might, and the research should continue. And if it holds promise, it WILL continue with or without Federal money.

8/11/2006 6:51 AM  
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